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That means it has oxidized

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Ferritinophagy is involved in iron-overloaded EMFF-induced ferroptosis in granulosa cells To further explore the mechanism of ferroptosis in granulosa cells induced by iron-overloaded EMFF, we studied clinical samples and examined the indicators of iron metabolism and ferroptosis in EMFF and granulosa cells from patients with EMs-related infertility

Its role in oxidative stress and cellular antioxidant defense is well-characterized